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Path Of Exile 2 Strategy For Killing Siora Blade Of The Mists Is Worth Your Attention - Location & Battle Strategy

Act 4 has been added to the current version of PoE 2, which features a new boss called Siora, Blade of the Mists. This guide will explain the specifics of this encounter, including its location, combat moves, and strategies.

Sep 05, 2025 Author: EZG

In Path of Exile 2 patch 0.3.0 released on August 29, the new Act 4 was introduced into the game, which is an island-themed game content. The main questline included in this Act will allow you to recruit Ezomytes, which is an important step in entering Interludes and exploring the endgame content.

However, before you can start this quest, you must first complete an encounter with Siora, Blade of the Mists, a new boss added in patch 0.3.0, who is a powerful and elusive enemy. After you activate all Megaliths and reach the designated arena, she will appear and start attacking you.

But I need to remind you here that if you are not ready for the battle, please try not to step into it, because Interludes in Path of Exile 2 are open and you can start the battle at any time instead of confronting it head-on. 

Path Of Exile 2 Strategy For Killing Siora Blade Of The Mists Is Worth Your Attention - Location & Battle Strategy

However, if you have this guide, you will get twice the result with half the effort. Here, we’ll provide you with specific instructions for finding Siora, Blade of the Mists, as well as strategies to use during the fight. Without further ado, let’s begin our exploration!

Location

First, let’s check out the location of this boss - in Stones of Serle map. Recruit the Ezomytes quest is automatically triggered after you enter the first Interlude, and requires you to go to the edge of the map and activate all the Megaliths in turn.

After you activate it, Siora will appear in the center of the entire map. At the same time, your small map will also change so that you can find her smoothly. However, according to some players’ feedback, this boss does not always spawn in the center of the map.

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If you farm it multiple times for PoE 2 Currency and loot it provides you, it is possible that it will appear from the circle of megaliths. Due to the changes to the game content in POE 2 0.3.0 patch, the edges of the arena in this encounter are not very clear, so please walk towards the boss when you are ready, otherwise you are likely to suffer strong damage.

Combat Moves

When you enter the arena where you fight Siora, Blade of the Mists, you’ll find that you can only move within a small circle, and the rest of the area is shrouded in dark fog, which is quite consistent with her title. The following are the boss’s attack moves summarized based on player feedback.

  • 1. Siora will launch a lightning-based attack first—five bolts of lightning will appear around her. But don’t worry too much, as you’ll receive a dodge reminder, giving you plenty of time to use skills or dodge away from these dangers.
  • 2. The boss will then cover the entire arena in darkness, which will cause you to continue to receive damage in the dark. So run towards Megalith, which is shining brightly, as much as possible, which will reduce the damage you suffer.
  • 3. Siora will also spin wildly on the ground and swing her scythe, which will cause continuous and large amounts of damage. The advice you can provide here is to stay away from her position as much as possible and dodge in time.
  • 4. As the battle progresses, the lightning cast by the boss will become more and more frequent, and it will appear more and more frequently. Move in time to avoid being hit by them.
  • 5. During the battle, Invincible spirits will occasionally spawn at the edge of the arena and fire bolts of energy at you. Although their damage is not as strong as the boss itself, you still need to pay attention to them.

Killing Strategy

From the above analysis of the moves, it’s clear that you need to maximize your Lightning Resistance build to achieve sustained combat. Also, try to stack as many affixes as possible that provide you with super high mobility, and spend a lot of POE 2 in-game currency to maximize it, which is very useful for avoiding damage.

Additionally, a constant shower of lightning will occur when its health drops to around 50%, so be careful when approaching this stage. Although Siora’s attack moves and damage capabilities are not as deadly as Viper Napuatzi, once your character is struck by its lightning, it will be very difficult to kill it in one go, so keeping moving and attacking frequently is the most important way to win this encounter.

Successfully defeating Siora, Blade of the Mists will net you a wealth of loot, and Una will appear after the battle. After speaking with her, you’ll be able to journey through Darkness of Scorched Farmlands and begin further exploration. This concludes the process of defeating Siora, Blade of the Mists in PoE 2. Hopefully, this guide will help you navigate this encounter more smoothly and earn you the generous rewards. Have fun!

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